Raised cardiac troponins

Cardiac troponins.

Cardiac troponins

Objective: To review the use of cardiac troponins as biomarkers for myocardial injury in human and veterinary medicine. Data sources: Data sources included scientific reviews and original research publications. Human data synthesis: Cardiac troponins have been extensively studied in human medicine. Finding an elevated cardiac troponin level carries important diagnostic and prognostic informatio...

Cardiac troponins in intensive care

The cardiac troponins are integral components of the myofibrillary apparatus and they regulate muscle contraction. The measurement of cardiac troponins has replaced other biomarkers for the specific detection of myocardial necrosis and for the diagnosis of myocardial infarction. The tissue specificity plus sensitivity of the measurement technology has meant that cardiac damage can be detected i...

High-sensitivity assays for cardiac troponins.

This issue of Clinical Chemistry and Laboratory Medicine (CCLM) devotes a large section to the cardiac troponins (cTn) and in particular to the impact of the novel high sensitivity (hs) assays on clinical practice. Furthermore, several articles deal with known or novel pitfalls of hs-cTn in clinical diagnostics. While there is no doubt that the hs-cTn assays constitute a significant analytical ...

Circulating Cardiac Troponins in Small Animals

INTRODUCTION The cardiac troponins I, T, and C (cTnI, cTnT, and cTnC) are thin filament-associated regulatory proteins of the heart muscle. They are crucial to the interaction between actin and myosin and occur at regular intervals of 38 nm along the tropomyosin molecule. Cardiac troponin I ("I" for inhibition) is uniquely expressed in the myocardium and is a potent inhibitor of the process of ...